Redistribution of canalicular organic anion transport activity in isolated and cultured rat hepatocytes

The hepatocanalicular transport of a large number of organic anions, such as bilirubin glucuronides and glutathione conjugates in the rat, is mediated by an adenosine triphosphate (ATP)‐dependent transport system, which is termed canalicular multispecific organic anion transporter (cMOAT). This syst...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 1995-06, Vol.21 (6), p.1649-1657
Hauptverfasser:	Roelofsen, Han, Bakker, Conny T. M., Schoemaker, Berry, Heijn, Marc, Jansen, Peter L. M., Oude Elferink, Ronald P. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloids - pharmacology Animals Anion Transport Proteins Bile Canaliculi - metabolism Biological and medical sciences Biological Transport Carrier Proteins - metabolism Cell Membrane - metabolism Cells, Cultured Fundamental and applied biological sciences. Psychology Glutathione - analogs & derivatives Glutathione - metabolism Kinetics Liver - drug effects Liver - metabolism Liver. Bile. Biliary tracts Male Methylamines - pharmacology Mice Mice, Mutant Strains Monensin - pharmacology Protein Kinase C - antagonists & inhibitors Rats Rats, Wistar Staurosporine Temperature Tetradecanoylphorbol Acetate - pharmacology Vertebrates: digestive system
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