Transforming growth factor‐β1 and mannose 6‐phosphate/insulin‐like growth factor‐II receptor expression during intrahepatic bile duct hyperplasia and biliary fibrosis in the rat

These studies investigate the role of transforming growth factor‐β1, a potent inhibitor of epithelial cell proliferation and stimulator of extracellular matrix biosynthesis, during intrahepatic bile duct hyperplasia and biliary fibrosis. These pathogenic responses were induced in rats by common bile...

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Veröffentlicht in:Hepatology (Baltimore, Md.) Md.), 1994-02, Vol.19 (2), p.412-417
Hauptverfasser: Saperstein, Lawrence A., Jirtle, Randy L., Farouk, Marwan, Thompson, Hugh J., Chung, Kyung S., Meyers, William C.
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Sprache:eng
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