Laryngeal preservation by induction chemotherapy plus radiotherapy in locally advanced head and neck cancer: The M. D. Anderson cancer center experience

Standard treatment of locally advanced laryngeal, hypopharyngeal, and some oropharyngeal cancers includes total laryngectomy. In an attempt to preserve the larynx through induction chemotherapy, we conducted two consecutive phase II studies. From March 1986 to February 1991, 64 patients with advance...

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Veröffentlicht in:	Head & neck 1994-01, Vol.16 (1), p.39-44
Hauptverfasser:	Shirinian, Mihran H., Weber, Randal S., Lippman, Scott M., Dimery, Isaiah W., Earley, Charles L., Garden, Adam S., Michaelson, Jacqueline, Morrison, William H., Kramer, Alan, Byers, Robert, Peters, Lester, Hong, Waun Ki, Goepfert, Helmuth
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Bleomycin - administration & dosage Bleomycin - adverse effects Carcinoma, Squamous Cell - drug therapy Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - radiotherapy Cisplatin - administration & dosage Cisplatin - adverse effects Clinical Protocols Combined Modality Therapy Ent and stomatology Female Fluorouracil - administration & dosage Fluorouracil - adverse effects Follow-Up Studies Humans Hypopharyngeal Neoplasms - drug therapy Hypopharyngeal Neoplasms - pathology Hypopharyngeal Neoplasms - radiotherapy Laryngeal Neoplasms - drug therapy Laryngeal Neoplasms - pathology Laryngeal Neoplasms - radiotherapy Laryngectomy Larynx - pathology Male Medical sciences Middle Aged Neoplasm Staging Oropharyngeal Neoplasms - drug therapy Oropharyngeal Neoplasms - pathology Oropharyngeal Neoplasms - radiotherapy Prospective Studies Radiotherapy Dosage Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Remission Induction Survival Rate
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