N-[4-(dicyanomethylazo)phenyl]-2-saccharin-2-ylacetamide in the synthesis of pyridazine and pyrimidine derivatives
N‐[4‐(Dicyanomethylazo)phenyl]‐2‐saccharin‐2‐ylacetamide (2) proved to be a convenient precursor for the synthesis of a variety of pyridazine and pyrimidine derivatives 4a,b,6, and 7. Also a series of substituted pyrimidines 10–16 were prepared from the reaction of N‐[4‐(2‐amino‐1‐cyano‐2‐substitute...
Gespeichert in:
| Veröffentlicht in: | Heteroatom chemistry 2004, Vol.15 (1), p.2-8 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 8 |
|---|---|
| container_issue | 1 |
| container_start_page | 2 |
| container_title | Heteroatom chemistry |
| container_volume | 15 |
| creator | Aly, A. A. Nassar, S. A. |
| description | N‐[4‐(Dicyanomethylazo)phenyl]‐2‐saccharin‐2‐ylacetamide (2) proved to be a convenient precursor for the synthesis of a variety of pyridazine and pyrimidine derivatives 4a,b,6, and 7. Also a series of substituted pyrimidines 10–16 were prepared from the reaction of N‐[4‐(2‐amino‐1‐cyano‐2‐substitutedvinylazo)phenyl]‐2‐(saccharin‐2‐yl)acetamide 9a,b with different reagents via initial addition to either the cyano or amino group, followed by cyclization. Some of the synthesized heterocycles were screened for their biological activity. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 15:2–8, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10194 |
| doi_str_mv | 10.1002/hc.10194 |
| format | Article |
| fullrecord | <record><control><sourceid>istex_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1002_hc_10194</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>ark_67375_WNG_TVXNM14V_J</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4014-366f4229f7a2db7a7db351528b22f040ba381281d57dfd74ed06293b7867885e3</originalsourceid><addsrcrecordid>eNp1kF1LwzAYhYMoOKfgT-jlvIjmq016KUM3Zc6bOQWRkCYpjXbtSMq0-_W2m3gheHXO4Ty8vBwAzjG6xAiRq0J3ilN2AAYYpQJixPFh7xmBHCf0GJyE8I4QxiwVA-Dn8JXBkXG6VVW9sk3RlmpbX6wLW7XlGyQwKK0L5V3V-a7TtlErZ2zkqqgpbBTaqpPgQlTn0br1zqitq2ykKrOLHdtHY73bqMZtbDgFR7kqgz370SF4ur1ZjKdw9ji5G1_PoGYIM0iTJGeEpDlXxGRccZPRGMdEZITkiKFMUYGJwCbmJjecWYMSktKMi4QLEVs6BKP9Xe3rELzN5bp7R_lWYiT7rWSh5W6rDoV79NOVtv2Xk9PxH96Fxn798sp_yIRTHsvn-UQuli_zB8yW8p5-Aw58eig</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>N-[4-(dicyanomethylazo)phenyl]-2-saccharin-2-ylacetamide in the synthesis of pyridazine and pyrimidine derivatives</title><source>Free E-Journal (出版社公開部分のみ）</source><source>Alma/SFX Local Collection</source><creator>Aly, A. A. ; Nassar, S. A.</creator><creatorcontrib>Aly, A. A. ; Nassar, S. A.</creatorcontrib><description>N‐[4‐(Dicyanomethylazo)phenyl]‐2‐saccharin‐2‐ylacetamide (2) proved to be a convenient precursor for the synthesis of a variety of pyridazine and pyrimidine derivatives 4a,b,6, and 7. Also a series of substituted pyrimidines 10–16 were prepared from the reaction of N‐[4‐(2‐amino‐1‐cyano‐2‐substitutedvinylazo)phenyl]‐2‐(saccharin‐2‐yl)acetamide 9a,b with different reagents via initial addition to either the cyano or amino group, followed by cyclization. Some of the synthesized heterocycles were screened for their biological activity. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 15:2–8, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10194</description><identifier>ISSN: 1042-7163</identifier><identifier>EISSN: 1098-1071</identifier><identifier>DOI: 10.1002/hc.10194</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><ispartof>Heteroatom chemistry, 2004, Vol.15 (1), p.2-8</ispartof><rights>Copyright © 2003 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4014-366f4229f7a2db7a7db351528b22f040ba381281d57dfd74ed06293b7867885e3</citedby><cites>FETCH-LOGICAL-c4014-366f4229f7a2db7a7db351528b22f040ba381281d57dfd74ed06293b7867885e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4010,27900,27901,27902</link.rule.ids></links><search><creatorcontrib>Aly, A. A.</creatorcontrib><creatorcontrib>Nassar, S. A.</creatorcontrib><title>N-[4-(dicyanomethylazo)phenyl]-2-saccharin-2-ylacetamide in the synthesis of pyridazine and pyrimidine derivatives</title><title>Heteroatom chemistry</title><addtitle>Heteroatom Chem</addtitle><description>N‐[4‐(Dicyanomethylazo)phenyl]‐2‐saccharin‐2‐ylacetamide (2) proved to be a convenient precursor for the synthesis of a variety of pyridazine and pyrimidine derivatives 4a,b,6, and 7. Also a series of substituted pyrimidines 10–16 were prepared from the reaction of N‐[4‐(2‐amino‐1‐cyano‐2‐substitutedvinylazo)phenyl]‐2‐(saccharin‐2‐yl)acetamide 9a,b with different reagents via initial addition to either the cyano or amino group, followed by cyclization. Some of the synthesized heterocycles were screened for their biological activity. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 15:2–8, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10194</description><issn>1042-7163</issn><issn>1098-1071</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><recordid>eNp1kF1LwzAYhYMoOKfgT-jlvIjmq016KUM3Zc6bOQWRkCYpjXbtSMq0-_W2m3gheHXO4Ty8vBwAzjG6xAiRq0J3ilN2AAYYpQJixPFh7xmBHCf0GJyE8I4QxiwVA-Dn8JXBkXG6VVW9sk3RlmpbX6wLW7XlGyQwKK0L5V3V-a7TtlErZ2zkqqgpbBTaqpPgQlTn0br1zqitq2ykKrOLHdtHY73bqMZtbDgFR7kqgz370SF4ur1ZjKdw9ji5G1_PoGYIM0iTJGeEpDlXxGRccZPRGMdEZITkiKFMUYGJwCbmJjecWYMSktKMi4QLEVs6BKP9Xe3rELzN5bp7R_lWYiT7rWSh5W6rDoV79NOVtv2Xk9PxH96Fxn798sp_yIRTHsvn-UQuli_zB8yW8p5-Aw58eig</recordid><startdate>2004</startdate><enddate>2004</enddate><creator>Aly, A. A.</creator><creator>Nassar, S. A.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>2004</creationdate><title>N-[4-(dicyanomethylazo)phenyl]-2-saccharin-2-ylacetamide in the synthesis of pyridazine and pyrimidine derivatives</title><author>Aly, A. A. ; Nassar, S. A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4014-366f4229f7a2db7a7db351528b22f040ba381281d57dfd74ed06293b7867885e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Aly, A. A.</creatorcontrib><creatorcontrib>Nassar, S. A.</creatorcontrib><collection>Istex</collection><collection>CrossRef</collection><jtitle>Heteroatom chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aly, A. A.</au><au>Nassar, S. A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>N-[4-(dicyanomethylazo)phenyl]-2-saccharin-2-ylacetamide in the synthesis of pyridazine and pyrimidine derivatives</atitle><jtitle>Heteroatom chemistry</jtitle><addtitle>Heteroatom Chem</addtitle><date>2004</date><risdate>2004</risdate><volume>15</volume><issue>1</issue><spage>2</spage><epage>8</epage><pages>2-8</pages><issn>1042-7163</issn><eissn>1098-1071</eissn><abstract>N‐[4‐(Dicyanomethylazo)phenyl]‐2‐saccharin‐2‐ylacetamide (2) proved to be a convenient precursor for the synthesis of a variety of pyridazine and pyrimidine derivatives 4a,b,6, and 7. Also a series of substituted pyrimidines 10–16 were prepared from the reaction of N‐[4‐(2‐amino‐1‐cyano‐2‐substitutedvinylazo)phenyl]‐2‐(saccharin‐2‐yl)acetamide 9a,b with different reagents via initial addition to either the cyano or amino group, followed by cyclization. Some of the synthesized heterocycles were screened for their biological activity. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 15:2–8, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10194</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><doi>10.1002/hc.10194</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1042-7163 |
| ispartof | Heteroatom chemistry, 2004, Vol.15 (1), p.2-8 |
| issn | 1042-7163 1098-1071 |
| language | eng |
| recordid | cdi_crossref_primary_10_1002_hc_10194 |
| source | Free E-Journal (出版社公開部分のみ）; Alma/SFX Local Collection |
| title | N-[4-(dicyanomethylazo)phenyl]-2-saccharin-2-ylacetamide in the synthesis of pyridazine and pyrimidine derivatives |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-01T07%3A37%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-istex_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=N-%5B4-(dicyanomethylazo)phenyl%5D-2-saccharin-2-ylacetamide%20in%20the%20synthesis%20of%20pyridazine%20and%20pyrimidine%20derivatives&rft.jtitle=Heteroatom%20chemistry&rft.au=Aly,%20A.%20A.&rft.date=2004&rft.volume=15&rft.issue=1&rft.spage=2&rft.epage=8&rft.pages=2-8&rft.issn=1042-7163&rft.eissn=1098-1071&rft_id=info:doi/10.1002/hc.10194&rft_dat=%3Cistex_cross%3Eark_67375_WNG_TVXNM14V_J%3C/istex_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |