Testing linkage and Gene × Environment interaction: Comparison of different affected sib-pair methods

The aim of this study was to compare, under different models of gene‐environment (G × E) interaction, the power to detect linkage and G × E interaction of different tests using affected sib‐pairs. Methods considered were: 1) the maximum likelihood lod‐score (MLS), based on the distribution of parent...

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Veröffentlicht in:	Genetic epidemiology 2003-07, Vol.25 (1), p.73-79
Hauptverfasser:	Dizier, M.H., Selinger-Leneman, H., Genin, E.
Format:	Artikel
Sprache:	eng
Schlagworte:	affected sib-pair alleles identical by descent gene×environment interaction maximum likelihood lodscore
Online-Zugang:	Volltext
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