Hepatic microsomal cytochrome P450S and chlorinated hydrocarbons in largha and ribbon seals from Hokkaido, Japan: Differential response of seal species to ah receptor agonist exposure

From 16 largha seals (Phoca larghá) and 15 ribbon seals (Phoca fasciata) in the coastal waters of Hokkaido, Japan, blubber chlorinated hydrocarbon (CHC) levels and hepatic cytochrome P450 (CYP) catalytic activities and their immunochemically detected protein content levels were measured. Concentrati...

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Veröffentlicht in:	Environmental toxicology and chemistry 2002-04, Vol.21 (4), p.794-806
Hauptverfasser:	Chiba, Issei, Sakakibara, Akihito, Iwata, Hisato, Ishizuka, Mayumi, Tanabe, Shinsuke, Akahori, Fumiaki, Kazusaka, Akio, Fujita, Shoichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - chemistry Animal, plant and microbial ecology Animals Applied ecology Biological and medical sciences Chlorinated hydrocarbon pesticide Cytochrome P-450 Enzyme System - pharmacology Cytochrome P450 Ecotoxicology, biological effects of pollution Environmental Exposure Enzyme Induction Female Fundamental and applied biological sciences. Psychology Insecticides - adverse effects Male Microsomes, Liver - enzymology Polychlorinated biphenyl Polychlorinated Biphenyls - adverse effects Seal Seals, Earless Techniques Toxic equivalent Water Pollutants, Chemical - adverse effects
Online-Zugang:	Volltext
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