Detection of mutagenic activity in the urine of rodents treated with p-rosaniline

p‐Rosaniline was fed to male and female Fischer 344 rats and B6C3F1 mice at doses of 1,000 and 2,000 ppm for male rats and 500 and 1,000 ppm for female rats and mice of both sexes. Urine was collected overnight at 1‐wk intervals over a 4‐wk treatment period and frozen until its use in the mutagenici...

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