Blockade of bradykinin receptors or angiotensin II type 2 receptor prevents paclitaxel‐associated acute pain syndrome in mice

Background Paclitaxel (PCX) is the first‐line choice for the treatment of several types of cancer, including breast, ovarian, and lung cancers. However, patients who receive even a single dose with PCX commonly develop mechanical and cold allodynia, a symptom known as PCX‐associated acute pain syndr...

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Veröffentlicht in:European journal of pain 2021-01, Vol.25 (1), p.189-198
Hauptverfasser: Zanata, Graziele C., Pinto, Larissa G., Silva, Nicole R., Lopes, Alexandre H. P., Oliveira, Francisco F. B., Schivo, Ieda R. S., Cunha, Fernando Q., McNaughton, Peter, Cunha, Thiago M., Silva, Rangel L.
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Sprache:eng
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