Copper‐Catalyzed A 3 ‐Coupling for the Diversity‐Oriented Synthesis of Proline‐Derived Alkynyl‐Substituted Peptidomimetic Scaffolds

The Aldehyde–Amine–Alkyne reaction (A 3 ) proves to be a powerful methodology as a coupling step of the Build/Couple/Pair approach in Diversity Oriented Synthesis (DOS) because it can lead to the formation of polyfunctionalized intermediates suitable for the creation of different molecular entities....

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Veröffentlicht in:	European journal of organic chemistry 2019-09, Vol.2019 (36), p.6203-6210
Hauptverfasser:	Innocenti, Riccardo, Lenci, Elena, Baldini, Lorenzo, Faggi, Cristina, Menchi, Gloria, Trabocchi, Andrea
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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