A Diels-Alder Reaction for the Total Synthesis of the Novel Antibiotic Antitumor Agent Mensacarcin

The antibiotic mensacarcin (1), which contains nine stereogenic centers and two epoxy functionalities, is a novel antitumor agent that was first isolated from the culture broth of Streptomyces sp. Gö C4/4 found in a soil sample next to the northern cafeteria of the University of Göttingen. For the s...

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Veröffentlicht in:	European Journal of Organic Chemistry 2005-06, Vol.2005 (12), p.2459-2467
Hauptverfasser:	Tietze, Lutz F., Güntner, Carlos, Gericke, Kersten M., Schuberth, Ingrid, Bunkoczi, Gabor
Format:	Artikel
Sprache:	eng
Schlagworte:	Antitumor agents Cycloadditions Electrocyclic reactions Epoxidation Natural products
Online-Zugang:	Volltext
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