Synthesis of New Tetrazole-Substituted Pyroaminoadipic and Pipecolic Acid Derivatives

Racemic 5‐aryl‐ and 5‐(arylmethyl)tetrazolyl‐substituted pyroaminoadipic and pipecolic acid derivatives were diastereoselectively synthesized from dimethyl meso‐2,5‐dibromoadipate (1) in good yields under mild reaction conditions. The key step of this reaction sequence is the selective N2‐alkylation...

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Veröffentlicht in:European journal of organic chemistry 2005-01, Vol.2005 (2), p.326-333
Hauptverfasser: Lenda, Fatimazohra, Guenoun, Farhate, Tazi, Bouchra, Ben larbi, Najib, Allouchi, Hassan, Martinez, Jean, Lamaty, Frédéric
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Sprache:eng
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