Efficient DNA Cleavage Induced by Copper(II) Complexes of Hydrolysis Derivatives of 2,4,6-Tri(2-pyridyl)-1,3,5-triazine in the Presence of Reducing Agents

The reaction of 2,4,6‐tri(pyridyl)‐1,3,5‐triazine (ptz) and copper(II) salts in dmf/water (1:1) results in the hydrolysis of ptz and formation of the anions bis(2‐pyridylcarbonyl)amide (ptO2–) and bis(2‐pyridylamine)amide (ptN2–), which are found in the complexes [Cu(ptN2)(OAc)]·3H2O (1), [Cu(ptO2)(...

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Veröffentlicht in:	European Journal of Inorganic Chemistry 2007-02, Vol.2007 (6), p.822-834
Hauptverfasser:	Borrás, Joaquín, Alzuet, Gloria, González-Alvarez, Marta, García-Giménez, Jose L., Macías, Benigno, Liu-González, Malva
Format:	Artikel
Sprache:	eng
Schlagworte:	Copper triazine complexes Oxidation Oxidative DNA damage ROS scavengers
Online-Zugang:	Volltext
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