CBA / J mice generate protective immunity to soluble A g85 but fail to respond efficiently to A g85 during natural M ycobacterium tuberculosis infection

In CBA/J mice, susceptibility to M ycobacterium tuberculosis ( M .tb ) is associated with low interferon‐gamma ( IFN ‐γ) responses to antigens ( A ntigen 85 ( A g85) and early secreted antigenic target‐6 (ESAT‐6)) that have been defined as immunodominant. Here, we asked whether the failure of CBA/J...

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Veröffentlicht in:	European journal of immunology 2012-04, Vol.42 (4), p.870-879
Hauptverfasser:	Beamer, Gillian L., Cyktor, Joshua, Flaherty, David K., Stromberg, Paul C., Carruthers, Bridget, Turner, Joanne
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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