Modulation of c‐fos and c‐myc mRNA levels in normal human lymphocytes by calcium ionophore A23187 and phorbol ester

A transient expression of the proto‐oncogenes c‐fos and c‐myc is rapidly induced by growth factors or mitogens in different cell types including lectin‐stimulated lymphocytes. To elucidate the early events of lymphocyte activation, we determined (by Northern blot analysis) the steady‐state levels of...

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Veröffentlicht in:	European journal of immunology 1986, Vol.16 (10), p.1217-1221
Hauptverfasser:	David Grausz, J., Fradelizi, Didier, Dautry, François, Monier, Roger, Lehn, Pierre
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of the immune response. Humoral and cellular immunity Antigens, Differentiation, T-Lymphocyte Antigens, Surface - immunology Biological and medical sciences Calcimycin - pharmacology Egtazic Acid - pharmacology Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Immunobiology Lymphocyte Activation - drug effects Lymphocytes - drug effects Lymphocytes - metabolism Organs and cells involved in the immune response Protein Kinase C - physiology Proto-Oncogenes RNA, Messenger - metabolism Tetradecanoylphorbol Acetate - pharmacology
Online-Zugang:	Volltext
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