Analysis of novel alleles of brother of tout-velu, the drosophila ortholog of human EXTL3 using a newly developed FRT42D ovo D chromosome

The FLP/FRT system permits rapid phenotypic screening of homozygous lethal mutations in the context of a viable mosaic fly. Combining this system with ovo dominant female-sterile transgenes enables efficient production of embryos derived from mutant germline clones lacking maternal contribution from...

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Veröffentlicht in:	Genesis (New York, N.Y. : 2000) N.Y. : 2000), 2016-11, Vol.54 (11), p.573-581
Hauptverfasser:	Lujan, Ernesto, Bornemann, Douglas J, Rottig, Carmen, Bayless, Brian A, Stocker, Hugo, Hafen, Ernst, Arora, Kavita, Warrior, Rahul
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Animals Body Patterning - genetics Drosophila melanogaster - genetics Drosophila melanogaster - growth & development Drosophila Proteins - genetics Female Gene Expression Regulation, Developmental Germ-Line Mutation - genetics Humans Infertility, Female - genetics Male Mosaicism - embryology N-Acetylglucosaminyltransferases - genetics Phenotype Synthetic Lethal Mutations - genetics Transgenes
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