Conditional restoration and inactivation of R bm47 reveal its tissue‐context requirement for viability and growth

Rbm47 encodes a RNA binding protein that is necessary for Cytidine to Uridine RNA editing. Rbm47 gt/gt mutant mice that harbor inactivated Rbm47 display poor viability. Here it was determined that the loss of Rbm47 gt/gt offspring is due to embryonic lethality at mid‐gestation. It was further showed...

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Veröffentlicht in:Genesis (New York, N.Y. : 2000) N.Y. : 2000), 2016-03, Vol.54 (3), p.115-122
Hauptverfasser: Fossat, Nicolas, Radziewic, Tania, Jones, Vanessa, Tourle, Karin, Tam, Patrick P. L.
Format: Artikel
Sprache:eng
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