Syndactyly and preaxial synpolydactyly in the single Sfrp 2 deleted mutant mice

Secreted Frizzled‐related protein 2 (Sfrp2) or Stromal Cell Derived Factor‐5 (SDF‐5) is highly expressed in the developing limbs. Here we showed the single Sfrp2 inactivation in mice resulted in syndactyly and preaxial synpolydactyly, predominantly in the hindlimbs. Tails were often kinked. A penetr...

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Veröffentlicht in:	Developmental dynamics 2008-09, Vol.237 (9), p.2506-2517
Hauptverfasser:	Ikegawa, Masaya, Han, Hua, Okamoto, Akihiko, Matsui, Ryosuke, Tanaka, Masami, Omi, Natsue, Miyamae, Mahito, Toguchida, Junya, Tashiro, Kei
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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