Crim1 KST264/KST264 mice display a disruption of the Crim1 gene resulting in perinatal lethality with defects in multiple organ systems

Crim1 is a transmembrane protein, containing six vWF‐C type cysteine‐rich repeats, that tethers growth factors to the cell surface. A mouse line, KST264, generated in a LacZ insertion mutagenesis gene‐trap screen, was examined to elucidate Crim1 function in development. We showed that Crim1 KST264/K...

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Veröffentlicht in:	Developmental dynamics 2007-02, Vol.236 (2), p.502-511
Hauptverfasser:	Pennisi, David J., Wilkinson, Lorine, Kolle, Gabriel, Sohaskey, Michael L., Gillinder, Kevin, Piper, Michael J., McAvoy, John W., Lovicu, Frank J., Little, Melissa H.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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