Effect of repeated administration of clonidine on adrenergic, cholinergic (muscarinic), dopaminergic, and serotonergic receptors in brain regions of rats

Clonidine (0.1 mg/kg) or its vehicle was administered orally to rats for 2 months. A significant decrease in mean blood pressure was observed in clonidine treated rats. Chronic administration of clonidine in rats produced alterations in central receptors. In hypothalamus and medulla, clonidine in tr...

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Veröffentlicht in:	Drug development research 1991, Vol.22 (2), p.141-152
Hauptverfasser:	Gulati, Anil, Hussain, Ghazala, Srimal, Rikhab Chand
Format:	Artikel
Sprache:	eng
Schlagworte:	Antihypertensive agents Biological and medical sciences Bmax value Cardiovascular system Medical sciences Pharmacology. Drug treatments receptor binding receptor up-regulation
Online-Zugang:	Volltext
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