Current drug targets for Alzheimer's disease treatment

Alzheimer's disease (AD), the most common form of dementia among the elderly, is a progressive, degenerative disorder of the brain with a loss of memory and cognition. A defining characteristic of AD is the deposition of amyloid fibrils and neurofibrillary tangles in the brain of afflicted indi...

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Veröffentlicht in:	Drug development research 2002-07, Vol.56 (3), p.267-281
Hauptverfasser:	Lahiri, Debomoy K., Farlow, Martin R., Greig, Nigel H., Sambamurti, Kumar
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease amyloid anticholinesterases APP gene cholesterol cholinergic agents cholinomimetic drugs donepezil estrogen exelon galantamine microtubule-associated protein NSAIDs oxidative damage phenserine vaccine
Online-Zugang:	Volltext
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