Interaction of nocodazole with tubulin isotypes

Nocodazole is an anti‐mitotic drug that has long been used as an experimental tool in cell biology. Although nocodazole is known to bind with high affinity to tubulin and to inhibit microtubule assembly, very little has been done on its precise mechanism of action. In fact, its binding to the differ...

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Veröffentlicht in:	Drug development research 2002-02, Vol.55 (2), p.91-96
Hauptverfasser:	Xu, Keliang, Schwarz, Patricia M., Ludueña, Richard F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents binding affinity Biological and medical sciences fluorescence quenching General aspects isotypes Medical sciences nocodazole Pharmacology. Drug treatments tubulin
Online-Zugang:	Volltext
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