Clinical Pharmacogenetics Implementation Consortium ( CPIC ) Guideline for the Use of Potent Volatile Anesthetic Agents and Succinylcholine in the Context of RYR 1 or CACNA 1S Genotypes

The identification in a patient of 1 of the 50 variants in the RYR 1 or CACNA 1S genes reviewed here should lead to a presumption of malignant hyperthermia susceptibility (MHS). MHS can lead to life‐threatening reactions to potent volatile anesthetic agents or succinylcholine. We summarize evidence...

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Veröffentlicht in:	Clinical pharmacology and therapeutics 2019-06, Vol.105 (6), p.1338-1344
Hauptverfasser:	Gonsalves, Stephen G., Dirksen, Robert T., Sangkuhl, Katrin, Pulk, Rebecca, Alvarellos, Maria, Vo, Teresa, Hikino, Keiko, Roden, Dan, Klein, Teri E., Poler, S. Mark, Patel, Sephalie, Caudle, Kelly E., Gordon, Ronald, Brandom, Barbara, Biesecker, Leslie G.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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