Comparison of outcomes for elderly patients treated with weekly paclitaxel in combination with carboplatin versus the standard 3‐weekly paclitaxel and carboplatin for advanced nonsmall cell lung cancer

BACKGROUND. The purpose of this study was to compare the outcomes between elderly (aged ≥70 years) patients treated with paclitaxel on a weekly basis and with carboplatin (every 4 weeks) versus the standard 3‐weekly regimen of carboplatin and paclitaxel for first‐line therapy of advanced nonsmall ce...

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Veröffentlicht in:	Cancer 2008-08, Vol.113 (3), p.542-546
Hauptverfasser:	Ramalingam, Suresh, Perry, Michael C., La Rocca, Renato V., Rinaldi, David, Gable, Preston S., Tester, William J., Belani, Chandra P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences carboplatin Carboplatin - administration & dosage Carboplatin - adverse effects Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - mortality Carcinoma, Non-Small-Cell Lung - pathology Drug Administration Schedule elderly Female Humans Lung Neoplasms - drug therapy Lung Neoplasms - mortality Lung Neoplasms - pathology Male Medical sciences Neoplasm Staging nonsmall cell lung cancer paclitaxel Paclitaxel - administration & dosage Paclitaxel - adverse effects Pneumology Survival Analysis Treatment Outcome Tumors Tumors of the respiratory system and mediastinum weekly schedule
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