Severe enteropathy among patients with stage II/III colon cancer treated on a randomized trial of bolus 5-fluorouracil/leucovorin plus or minus oxaliplatin : A prospective analysis

Cases of severe gastrointestinal toxicity were monitored prospectively during NSABP C-07, a randomized clinical trial of adjuvant therapy for patients with stage II/III colon cancer. Patients were treated with weekly bolus 5-fluorouracil (5-FU) and leucovorin (FL; "Roswell Park Regimen") o...

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Veröffentlicht in:	Cancer 2007-11, Vol.110 (9), p.1945-1950
Hauptverfasser:	KUEBLER, J. Philip, COLANGELO, Linda, O'CONNELL, Michael J, SMITH, Roy E, YOTHERS, Greg, BEGOVIC, Mirsada, ROBINSON, Bridget, SEAY, Thomas E, WOLMARK, Norman
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Adenocarcinoma - pathology Aged Antineoplastic Combined Chemotherapy Protocols - adverse effects Biological and medical sciences Colonic Diseases - chemically induced Colonic Diseases - epidemiology Colonic Neoplasms - drug therapy Colonic Neoplasms - pathology Diarrhea - chemically induced Female Fluorouracil - administration & dosage Fluorouracil - adverse effects Gastroenterology. Liver. Pancreas. Abdomen Humans Leucovorin - administration & dosage Leucovorin - adverse effects Male Medical sciences Middle Aged Neoplasm Staging Organoplatinum Compounds - administration & dosage Organoplatinum Compounds - adverse effects Sex Factors Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors
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