Adjuvant postoperative radiotherapy for colon carcinoma
BACKGROUND The objective of this report was to review the role of adjuvant postoperative radiotherapy (RT) for patients with adenocarcinoma of the colon. METHODS The authors reviewed the pertinent literature. RESULTS Data suggested that locoregional postoperative RT improves both local control and s...
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| Veröffentlicht in: | Cancer 2004-09, Vol.101 (6), p.1338-1344 |
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| container_issue | 6 |
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| container_title | Cancer |
| container_volume | 101 |
| creator | Mendenhall, William M. Amos, E. Henry Rout, W. Robert Zlotecki, Robert A. Hochwald, Steven N. Cance, William G. |
| description | BACKGROUND
The objective of this report was to review the role of adjuvant postoperative radiotherapy (RT) for patients with adenocarcinoma of the colon.
METHODS
The authors reviewed the pertinent literature.
RESULTS
Data suggested that locoregional postoperative RT improves both local control and survival for patients with T4N0–N1 tumors. There also may be a benefit for patients with T3N1–N2 tumors, but the data were equivocal. Whole abdominal RT may result in a similar benefit but is associated with increased toxicity.
CONCLUSIONS
Postoperative RT should be considered for patients with T4N0–N1 colon carcinoma. Locoregional fields should be used. Cancer 2004. © 2004 American Cancer Society.
Adjuvant postoperative radiotherapy probably improves locoregional control and survival for patients with T4 colon carcinoma. The benefit for patients with T3N1–N2 disease is equivocal. |
| doi_str_mv | 10.1002/cncr.20526 |
| format | Article |
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The objective of this report was to review the role of adjuvant postoperative radiotherapy (RT) for patients with adenocarcinoma of the colon.
METHODS
The authors reviewed the pertinent literature.
RESULTS
Data suggested that locoregional postoperative RT improves both local control and survival for patients with T4N0–N1 tumors. There also may be a benefit for patients with T3N1–N2 tumors, but the data were equivocal. Whole abdominal RT may result in a similar benefit but is associated with increased toxicity.
CONCLUSIONS
Postoperative RT should be considered for patients with T4N0–N1 colon carcinoma. Locoregional fields should be used. Cancer 2004. © 2004 American Cancer Society.
Adjuvant postoperative radiotherapy probably improves locoregional control and survival for patients with T4 colon carcinoma. The benefit for patients with T3N1–N2 disease is equivocal.</description><identifier>ISSN: 0008-543X</identifier><identifier>EISSN: 1097-0142</identifier><identifier>DOI: 10.1002/cncr.20526</identifier><identifier>PMID: 15316945</identifier><identifier>CODEN: CANCAR</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adenocarcinoma - radiotherapy ; Adenocarcinoma - surgery ; Biological and medical sciences ; chemotherapy ; colon carcinoma ; Colonic Neoplasms - radiotherapy ; Colonic Neoplasms - surgery ; Combined Modality Therapy ; Disease-Free Survival ; Humans ; Lymphatic Metastasis ; Medical sciences ; Postoperative Period ; radiotherapy ; Radiotherapy, Adjuvant ; Treatment Outcome ; treatment outcomes ; Tumors</subject><ispartof>Cancer, 2004-09, Vol.101 (6), p.1338-1344</ispartof><rights>Copyright © 2004 American Cancer Society</rights><rights>2004 INIST-CNRS</rights><rights>Copyright 2004 American Cancer Society.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4206-a750bafa9a1043a96d30d3c00eb10aa31f39323b455fe700cab730b19f9aa6f63</citedby><cites>FETCH-LOGICAL-c4206-a750bafa9a1043a96d30d3c00eb10aa31f39323b455fe700cab730b19f9aa6f63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fcncr.20526$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fcncr.20526$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,1432,27923,27924,45573,45574,46408,46832</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16076806$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15316945$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mendenhall, William M.</creatorcontrib><creatorcontrib>Amos, E. Henry</creatorcontrib><creatorcontrib>Rout, W. Robert</creatorcontrib><creatorcontrib>Zlotecki, Robert A.</creatorcontrib><creatorcontrib>Hochwald, Steven N.</creatorcontrib><creatorcontrib>Cance, William G.</creatorcontrib><title>Adjuvant postoperative radiotherapy for colon carcinoma</title><title>Cancer</title><addtitle>Cancer</addtitle><description>BACKGROUND
The objective of this report was to review the role of adjuvant postoperative radiotherapy (RT) for patients with adenocarcinoma of the colon.
METHODS
The authors reviewed the pertinent literature.
RESULTS
Data suggested that locoregional postoperative RT improves both local control and survival for patients with T4N0–N1 tumors. There also may be a benefit for patients with T3N1–N2 tumors, but the data were equivocal. Whole abdominal RT may result in a similar benefit but is associated with increased toxicity.
CONCLUSIONS
Postoperative RT should be considered for patients with T4N0–N1 colon carcinoma. Locoregional fields should be used. Cancer 2004. © 2004 American Cancer Society.
Adjuvant postoperative radiotherapy probably improves locoregional control and survival for patients with T4 colon carcinoma. The benefit for patients with T3N1–N2 disease is equivocal.</description><subject>Adenocarcinoma - radiotherapy</subject><subject>Adenocarcinoma - surgery</subject><subject>Biological and medical sciences</subject><subject>chemotherapy</subject><subject>colon carcinoma</subject><subject>Colonic Neoplasms - radiotherapy</subject><subject>Colonic Neoplasms - surgery</subject><subject>Combined Modality Therapy</subject><subject>Disease-Free Survival</subject><subject>Humans</subject><subject>Lymphatic Metastasis</subject><subject>Medical sciences</subject><subject>Postoperative Period</subject><subject>radiotherapy</subject><subject>Radiotherapy, Adjuvant</subject><subject>Treatment Outcome</subject><subject>treatment outcomes</subject><subject>Tumors</subject><issn>0008-543X</issn><issn>1097-0142</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9j11LwzAYhYMobk5v_AHSG2-EzjdJk6yXo_gFQ0EUvCtv0wQ7uqYk3WT_3s4WdufV4cDDOTyEXFOYUwB2rxvt5wwEkydkSiFVMdCEnZIpACxikfCvCbkIYd1XxQQ_JxMqOJVpIqZELcv1dodNF7UudK41HrtqZyKPZeW67762-8g6H2lXuybS6HXVuA1ekjOLdTBXY87I5-PDR_Ycr96eXrLlKtYJAxmjElCgxRQpJBxTWXIouQYwBQVETi1POeNFIoQ1CkBjoTgUNLUporSSz8jdsKu9C8Ebm7e-2qDf5xTyg31-sM__7Hv4ZoDbbbEx5REddXvgdgQwaKytx0ZX4chJUHIBhyE6cD9Vbfb_XObZa_Y-nP8CRBlx_g</recordid><startdate>20040915</startdate><enddate>20040915</enddate><creator>Mendenhall, William M.</creator><creator>Amos, E. Henry</creator><creator>Rout, W. Robert</creator><creator>Zlotecki, Robert A.</creator><creator>Hochwald, Steven N.</creator><creator>Cance, William G.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20040915</creationdate><title>Adjuvant postoperative radiotherapy for colon carcinoma</title><author>Mendenhall, William M. ; Amos, E. Henry ; Rout, W. Robert ; Zlotecki, Robert A. ; Hochwald, Steven N. ; Cance, William G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4206-a750bafa9a1043a96d30d3c00eb10aa31f39323b455fe700cab730b19f9aa6f63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Adenocarcinoma - radiotherapy</topic><topic>Adenocarcinoma - surgery</topic><topic>Biological and medical sciences</topic><topic>chemotherapy</topic><topic>colon carcinoma</topic><topic>Colonic Neoplasms - radiotherapy</topic><topic>Colonic Neoplasms - surgery</topic><topic>Combined Modality Therapy</topic><topic>Disease-Free Survival</topic><topic>Humans</topic><topic>Lymphatic Metastasis</topic><topic>Medical sciences</topic><topic>Postoperative Period</topic><topic>radiotherapy</topic><topic>Radiotherapy, Adjuvant</topic><topic>Treatment Outcome</topic><topic>treatment outcomes</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mendenhall, William M.</creatorcontrib><creatorcontrib>Amos, E. Henry</creatorcontrib><creatorcontrib>Rout, W. Robert</creatorcontrib><creatorcontrib>Zlotecki, Robert A.</creatorcontrib><creatorcontrib>Hochwald, Steven N.</creatorcontrib><creatorcontrib>Cance, William G.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mendenhall, William M.</au><au>Amos, E. Henry</au><au>Rout, W. Robert</au><au>Zlotecki, Robert A.</au><au>Hochwald, Steven N.</au><au>Cance, William G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Adjuvant postoperative radiotherapy for colon carcinoma</atitle><jtitle>Cancer</jtitle><addtitle>Cancer</addtitle><date>2004-09-15</date><risdate>2004</risdate><volume>101</volume><issue>6</issue><spage>1338</spage><epage>1344</epage><pages>1338-1344</pages><issn>0008-543X</issn><eissn>1097-0142</eissn><coden>CANCAR</coden><abstract>BACKGROUND
The objective of this report was to review the role of adjuvant postoperative radiotherapy (RT) for patients with adenocarcinoma of the colon.
METHODS
The authors reviewed the pertinent literature.
RESULTS
Data suggested that locoregional postoperative RT improves both local control and survival for patients with T4N0–N1 tumors. There also may be a benefit for patients with T3N1–N2 tumors, but the data were equivocal. Whole abdominal RT may result in a similar benefit but is associated with increased toxicity.
CONCLUSIONS
Postoperative RT should be considered for patients with T4N0–N1 colon carcinoma. Locoregional fields should be used. Cancer 2004. © 2004 American Cancer Society.
Adjuvant postoperative radiotherapy probably improves locoregional control and survival for patients with T4 colon carcinoma. The benefit for patients with T3N1–N2 disease is equivocal.</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>15316945</pmid><doi>10.1002/cncr.20526</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Wiley Free Content; Wiley Online Library All Journals; Alma/SFX Local Collection |
| subjects | Adenocarcinoma - radiotherapy Adenocarcinoma - surgery Biological and medical sciences chemotherapy colon carcinoma Colonic Neoplasms - radiotherapy Colonic Neoplasms - surgery Combined Modality Therapy Disease-Free Survival Humans Lymphatic Metastasis Medical sciences Postoperative Period radiotherapy Radiotherapy, Adjuvant Treatment Outcome treatment outcomes Tumors |
| title | Adjuvant postoperative radiotherapy for colon carcinoma |
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