Peptides Targeting RNA m 6 A Methylations Influence the Viability of Cancer Cells

N6-methyladenosine (m A) is the most abundant nucleotide modification observed in eukaryotic mRNA. Changes in m A levels in transcriptome are tightly correlated to expression levels of m A methyltransferases and demethylases. Abnormal expression levels of methyltransferases and demethylases are obse...

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Veröffentlicht in:	ChemMedChem 2023-02, Vol.18 (4), p.e202200549
Hauptverfasser:	Rauff, Rushdhi, Abedeera, Sudeshi M, Schmocker, Stefani, Xie, Jiale, Abeysirigunawardena, Sanjaya C
Format:	Artikel
Sprache:	eng
Schlagworte:	Alpha-Ketoglutarate-Dependent Dioxygenase FTO - metabolism Humans Male Methylation Methyltransferases - metabolism Neoplasms - drug therapy Neoplasms - metabolism RNA - metabolism RNA, Messenger - genetics
Online-Zugang:	Volltext
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