Front Cover: MPI8 is Potent against SARS‐CoV‐2 by Inhibiting Dually and Selectively the SARS‐CoV‐2 Main Protease and the Host Cathepsin L (ChemMedChem 1/2022)

The Front Cover shows that MPI8, a SARS‐CoV‐2 main protease inhibitor, dually inhibits human cathepsin L to prevent the SARS‐CoV‐2 RNA genome from leaving the endosome. MPI8 is a reversible covalent inhibitor of the SARS‐CoV‐2 main protease that displays high potency in inhibiting the virus in vitro...

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Veröffentlicht in:	ChemMedChem 2022-01, Vol.17 (1), p.n/a
Hauptverfasser:	Ma, Xinyu R., Alugubelli, Yugendar R., Ma, Yuying, Vatansever, Erol C., Scott, Danielle A., Qiao, Yuchen, Yu, Ge, Xu, Shiqing, Liu, Wenshe Ray
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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