Cover Picture: Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors (ChemMedChem 16/2016)

The front cover picture shows the heterodimeric structure of the HIV‐1 reverse transcriptase (RT) complexed with the RNA:DNA duplex. RT is a multifunctional enzyme endowed with several different functions, including the ribonuclease H (RNase H) activity responsible for the RNA strand hydrolysis of t...

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Veröffentlicht in:	ChemMedChem 2016-08, Vol.11 (16), p.1669-1669
Hauptverfasser:	Corona, Angela, Desantis, Jenny, Massari, Serena, Distinto, Simona, Masaoka, Takashi, Sabatini, Stefano, Esposito, Francesca, Manfroni, Giuseppe, Maccioni, Elias, Cecchetti, Violetta, Pannecouque, Christophe, Le Grice, Stuart F. J., Tramontano, Enzo, Tabarrini, Oriana
Format:	Artikel
Sprache:	eng
Schlagworte:	allosterism antiviral agents inhibitors medicinal chemistry ribonucleases
Online-Zugang:	Volltext
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