Dynamic Optimization of the PyNP/PNP Phosphorolytic Enzymatic Process Using MOSAICmodeling

Pyrimidine and purine nucleoside phosphorylases catalyze the reversible phosphorolytic cleavage and formation of the glycosidic bond of purine and pyrimidine nucleosides, respectively, and are thus, key catalysts for the synthesis of new compounds. The selection of the best combination of enzyme and...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Chemie ingenieur technik 2017-11, Vol.89 (11), p.1523-1533
Hauptverfasser:	Wilms, Terrance, Rischawy, Daniel Federico, Barz, Tilman, Esche, Erik, Repke, Jens‐Uwe, Wagner, Anke, Neubauer, Peter, Cruz Bournazou, Mariano Nicolas
Format:	Artikel
Sprache:	eng
Schlagworte:	Global optimality Mixed‐integer dynamic optimization Modified nucleosides Orthogonal collocation Process optimization Transglycosylation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!