ChemInform Abstract: Asymmetric Synthesis and Biological Evaluation of N-Cyclohexyl-4- [1-(2,4-dichlorophenyl)-1-(p-tolyl)methyl]piperazine-1-carboxamide as hCB1 Receptor Antagonists

Two enantiomers of the most potent racemic compounds in a series of recently discovered benzhydrylpiperazines are prepared using the Davis‐Ellmann‐type sulfonamide chemistry.

Bibliographische Detailangaben

Veröffentlicht in:	ChemInform 2012-03, Vol.43 (11), p.no-no
Hauptverfasser:	Gao, Linghuan, Li, Min, Meng, Tao, Peng, Hongli, Xie, Xin, Zhang, Yongliang, Jin, Yu, Wang, Xin, Zou, Libo, Shen, Jingkang
Format:	Artikel
Sprache:	eng
Schlagworte:	diastereoselective syntheses diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism) enantioselective syntheses (incl. cis/trans-isomerism) pyrazine derivatives receptor binding activity
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