H 2 O ⋅ B(C 6 F 5 ) 3 -Catalyzed para-Alkylation of Anilines with Alkenes Applied to Late-Stage Functionalization of Non-Steroidal Anti-Inflammatory Drugs

Anilines are core motifs in a variety of important molecules including medicines, materials and agrochemicals. We report a straightforward procedure that allows access to new chemical space of anilines via their para-C-H alkylation. The method utilizes commercially available catalytic H O ⋅ B(C F )...

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Veröffentlicht in:	Chemistry : a European journal 2024-03, Vol.30 (13), p.e202303130
Hauptverfasser:	Winfrey, Laura, Yun, Lei, Passeri, Ginevra, Suntharalingam, Kogularamanan, Pulis, Alexander P
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkenes - chemistry Alkylation Aniline Compounds - chemistry Anti-Inflammatory Agents, Non-Steroidal Catalysis
Online-Zugang:	Volltext
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