Synthesis of Enantiopure Homoallylic Alcohols and Ethers by Diastereoselective Allylation of Aldehydes

Enantiopure homoallylic alcohols 5, which are important building blocks in organic synthesis, are obtained with an ee of greater than 99% and a yield of 75–95% by cleavage of the secondary homoallylic ethers 4 using sodium in liquid ammonia. The ethers 4 are formed with excellent diastereoselectivit...

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Veröffentlicht in:	Chemistry : a European journal 1996-09, Vol.2 (9), p.1164-1172
Hauptverfasser:	Tietze, Lutz F., Schiemann, Kai, Wegner, Christoph, Wulff, Christian
Format:	Artikel
Sprache:	eng
Schlagworte:	allylations allylsilanes double stereodifferentiation ephedrine homoallylic alcohols
Online-Zugang:	Volltext
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