Dihydrogen‐Driven NADPH Recycling in Imine Reduction and P450‐Catalyzed Oxidations Mediated by an Engineered O 2 ‐Tolerant Hydrogenase

The O 2 ‐tolerant NAD + ‐reducing hydrogenase (SH) from Ralstonia eutropha ( Cupriavidus necator ) has already been applied in vitro and in vivo for H 2 ‐driven NADH recycling in coupled enzymatic reactions with various NADH‐dependent oxidoreductases. To expand the scope for application in NADPH‐dep...

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Veröffentlicht in:ChemCatChem 2020-10, Vol.12 (19), p.4853-4861
Hauptverfasser: Preissler, Janina, Reeve, Holly A., Zhu, Tianze, Nicholson, Jake, Urata, Kouji, Lauterbach, Lars, Wong, Luet L., Vincent, Kylie A., Lenz, Oliver
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Sprache:eng
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