Significant Discovery of Tetrahydrothieno[3,2‐c]pyridine‐2‐carboxamide Analogs as Potent P2Y12 Receptor Antagonists

A series of analogs containing tetrahydrothieno[3,2‐c]pyridine‐2‐carboxamide as a building block with numerous alicyclic and aromatic amines were synthesized. All analogs were characterized by spectral analysis and evaluated for their in vitro antiplatelet activity. 4‐Fluorophenyl amide derivatives...

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Veröffentlicht in:	Chemistry & biodiversity 2019-04, Vol.16 (4), p.e1800550-n/a
Hauptverfasser:	Bhalekar, Sujit B., Shelke, Sharad N.
Format:	Artikel
Sprache:	eng
Schlagworte:	antiplatelet activity biological activity Lipinski's rule prasugrel synthesis design tetrahydrothieno[3,2-c]pyridine
Online-Zugang:	Volltext
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