In vitro protein binding interaction studies involving cefixime

Cefixime is a new oral cephalosporin currently undergoing clinical trials. Selected agents with the likelihood for coadministration with cefixime in man were examined for their influence on the in vitro binding of cefixime in pooled serum from dog, monkey, and man. Results from these experiments sho...

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Veröffentlicht in:	Biopharmaceutics & drug disposition 1988-05, Vol.9 (3), p.315-320
Hauptverfasser:	Bialer, Meir, Wu, Wen Hui, Faulkner, Robert D., Michael Silber, B., Yacobi, Avraham
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Blood Proteins - metabolism Cefixime Cefotaxime - analogs & derivatives Cefotaxime - blood Cefotaxime - metabolism Dogs Drug Interactions Half-Life Humans In Vitro Techniques Macaca fascicularis Medical sciences Oral Cephalosporin Pharmacology. Drug treatments Protein Binding Protein binding interactions
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