A high‐throughput and simultaneous determination of combretastatin A‐4 phosphate and its metabolites in human plasma using HPLC–MS/MS: Application to a clinical pharmacokinetic study

To investigate the clinical pharmacokinetics of CA4P, a high‐throughput high‐performance liquid chromatography–tandem mass spectrometry assay with an identical positive electrospray ionization (ESI) mode was developed for the simultaneous determination of CA4P, its active metabolite CA4, and CA4 glu...

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Veröffentlicht in:	Biomedical chromatography 2021-11, Vol.35 (11), p.n/a
Hauptverfasser:	Wu, Qizhen, Wang, Qian, Wang, Yixuan, Huang, Jingqiu, Fang, Yalin, Wu, Weiyi, Wu, Wenying, Wu, Fanhong, Yu, Xiaodong, Sun, Yan
Format:	Artikel
Sprache:	eng
Schlagworte:	ammonium adduct ion, combretastatin, human plasma, LC–MS/MS, metabolite
Online-Zugang:	Volltext
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