Fermentation of Bacillus thuringiensis for exotoxin production: Process analysis study
The exotoxin produced by certain serotypes of Bacillus thuringiensis was used as a means of microbiological control of the larval development of flies. The optimal batch cultivation conditions with respect to pH, temperature, aeration, agitation, and initial concentration of growth‐limiting substrat...
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Veröffentlicht in: | Biotechnology and bioengineering 1980-08, Vol.22 (8), p.1707-1724 |
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container_title | Biotechnology and bioengineering |
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creator | Holmberg, Andrea Sievänen, Risto Carlberg, Gunnel |
description | The exotoxin produced by certain serotypes of Bacillus thuringiensis was used as a means of microbiological control of the larval development of flies. The optimal batch cultivation conditions with respect to pH, temperature, aeration, agitation, and initial concentration of growth‐limiting substrate were determined. A dynamic model describing the process was designed and fitted to the experimental data. The application of a method for estimating exotoxin and bacterial concentrations from on‐line measurable quantities such as oxygen consumption and heat production is presented. |
doi_str_mv | 10.1002/bit.260220812 |
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title | Fermentation of Bacillus thuringiensis for exotoxin production: Process analysis study |
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