Fatty acids may influence insulin dynamics through modulation of albumin-Zn 2+ interactions

Insulin is stored within the pancreas in an inactive Zn -bound hexameric form prior to release. Similarly, clinical insulins contain Zn and form multimeric complexes. Upon release from the pancreas or upon injection, insulin only becomes active once Zn disengages from the complex. In plasma and othe...

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Veröffentlicht in:	BioEssays 2021-12, Vol.43 (12), p.e2100172
Hauptverfasser:	Arya, Swati, Gourley, Adam J, Penedo, J Carlos, Blindauer, Claudia A, Stewart, Alan J
Format:	Artikel
Sprache:	eng
Schlagworte:	Albumins Diabetes Mellitus, Type 2 - drug therapy Fatty Acids Humans Insulin Zinc
Online-Zugang:	Volltext
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