Effects of 60 Hz 14 µT magnetic field on the apoptosis of testicular germ cell in mice

We recently reported that continuous exposure, for 8 weeks, of extremely low frequency (ELF) magnetic field (MF) of 0.1 or 0.5 mT might induce testicular germ cell apoptosis in BALB/c mice. In that report, the ELF MF exposure did not significantly affect the body weight or testicular weight, but sig...

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Veröffentlicht in:Bioelectromagnetics 2009-01, Vol.30 (1), p.66-72
Hauptverfasser: Kim, Yoon-Won, Kim, Hee-Sung, Lee, Jin-Sang, Kim, Young-Jin, Lee, Sang-Kon, Seo, Jae-Nam, Jung, Kyeong-Cheon, Kim, Nam, Gimm, Youn-Myoung
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Sprache:eng
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Zusammenfassung:We recently reported that continuous exposure, for 8 weeks, of extremely low frequency (ELF) magnetic field (MF) of 0.1 or 0.5 mT might induce testicular germ cell apoptosis in BALB/c mice. In that report, the ELF MF exposure did not significantly affect the body weight or testicular weight, but significantly increased the incidence of testicular germ cell death. In the present study, we aimed to further characterize the effect of a 16‐week continuous exposure to ELF MF of 14 or 200 µT on testicular germ cell apoptosis in mice. There were no significant effects of MF on body weight and testosterone levels in mice. In TUNEL staining (In situ terminal deoxynucleotidyl transferase‐mediated deoxy‐UTP nick end labeling), germ cells showed a significantly higher apoptotic rate in exposed mice than in sham controls (P 
ISSN:0197-8462
1521-186X
DOI:10.1002/bem.20448