Atrazine and reproductive function: mode and mechanism of action studies

Atrazine, a chlorotriazine herbicide, is used to control annual grasses and broadleaf weeds. In this review, we summarize our laboratory's work evaluating the neuroendocrine toxicity of atrazine (and related chlorotriazines) from an historic perspective. We provide the rationale for our work as...

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Veröffentlicht in:	Birth defects research. Part B. Developmental and reproductive toxicology 2007-04, Vol.80 (2), p.98-112
Hauptverfasser:	Cooper, Ralph L., Laws, Susan C., Das, Parikshit C., Narotsky, Michael G., Goldman, Jerome M., Lee Tyrey, E., Stoker, Tammy E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - physiology Animals Animals, Suckling atrazine Atrazine - toxicity Chlorine Compounds - toxicity Estrogens - physiology Female GnRH Herbicides - toxicity Hypothalamus - drug effects Hypothalamus - physiology Luteinizing Hormone - blood Mammary Neoplasms, Animal - chemically induced neuroendocrine Ovulation - blood Ovulation - drug effects Pituitary Gland - drug effects Pituitary Gland - physiology Pregnancy Pregnancy Maintenance - drug effects Pregnancy, Animal - drug effects Prolactin - secretion Rats Reproduction - drug effects Sexual Maturation - drug effects
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