Evaluation of two methods for assessing gene-environment interactions using data from the Danish case-control study of facial clefts

BACKGROUND Epidemiological investigations have begun to consider gene‐environment (GE) interactions as potential risk factors for many diseases, including several different birth defects. However, traditional methodological approaches for the analysis of case‐control data tend to have low power for...

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Veröffentlicht in:	Birth defects research. A Clinical and molecular teratology 2005-08, Vol.73 (8), p.541-546
Hauptverfasser:	Etheredge, Analee J., Christensen, Kaare, del Junco, Deborah, Murray, Jeffrey C., Mitchell, Laura E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities, Drug-Induced - epidemiology Abnormalities, Drug-Induced - genetics Biological and medical sciences birth defects Case-Control Studies Cleft Palate - epidemiology Cleft Palate - genetics Denmark Embryology: invertebrates and vertebrates. Teratology Environment Epidemiologic Methods epidemiology Female Fundamental and applied biological sciences. Psychology gene-environment interaction Genetic Variation genetics Genotype Humans log-linear model Male Pregnancy Research Design Teratology. Teratogens
Online-Zugang:	Volltext
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