Induced effect of Ca 2+ and Al 3+ on chaetominine synthesis by Aspergillus fumigatus CY018 under submerged fermentation

Chaetominine (CHA), an alkaloid with a biological activity obtained from Aspergillus fumigatus CY018, has strong anticancer activity against the human leukemia cells. However, its physiological and biochemical research is limited by CHA yield in the liquid-state fermentation, which is a problem that...

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Veröffentlicht in:	Biotechnology and applied biochemistry 2022-12, Vol.69 (6), p.2733-2744
Hauptverfasser:	Liu, Changqing, Chen, Tianwen, Chen, Jijie, Zhou, Yuxuan, Deng, Lina, Feng, Gongneng, Gao, Jian, Liang, Huixing
Format:	Artikel
Sprache:	eng
Schlagworte:	Aspergillus fumigatus - metabolism Bioreactors Fermentation Humans Indole Alkaloids - metabolism Indole Alkaloids - pharmacology
Online-Zugang:	Volltext
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