Efficacy and safety of intraarticular hylan or hyaluronic acids for osteoarthritis of the knee: A randomized controlled trial

Objective To compare the efficacy and safety of intraarticular hylan and 2 hyaluronic acids (HAs) in osteoarthritis (OA) of the knee. Methods This was a multicenter, patient‐blind, randomized controlled trial in 660 patients with symptomatic knee OA. Patients were randomly assigned to receive 1 cycl...

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Veröffentlicht in:	Arthritis and rheumatism 2007-11, Vol.56 (11), p.3610-3619
Hauptverfasser:	Jüni, Peter, Reichenbach, Stephan, Trelle, Sven, Tschannen, Beatrice, Wandel, Simon, Jordi, Beat, Züllig, Maya, Guetg, Reto, Jörg Häuselmann, Hans, Schwarz, Hans, Theiler, Robert, Ziswiler, Hans Rudolf, Dieppe, Paul A., Villiger, Peter M., Egger, Matthias
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - administration & dosage Adjuvants, Immunologic - adverse effects Aged Biocompatible Materials - administration & dosage Biocompatible Materials - adverse effects Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents Diseases of the osteoarticular system Female Humans Hyaluronic Acid - administration & dosage Hyaluronic Acid - adverse effects Hyaluronic Acid - analogs & derivatives Injections, Intra-Articular Male Medical sciences Middle Aged Miscellaneous. Osteoarticular involvement in other diseases Osteoarthritis Osteoarthritis, Knee - drug therapy Pain - drug therapy Pharmacology. Drug treatments Quality of Life Treatment Outcome
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