Methotrexate versus azathioprine in the treatment of rheumatoid arthritis. A forty‐eight–week randomized, double‐blind trial

We conducted a double‐blind, randomized trial comparing azathioprine (AZA) and methotrexate (MTX) in the treatment of patients with rheumatoid arthritis in whom parenteral gold and/or D‐penicillamine treatment had been unsuccessful. Patients were randomly assigned to receive either AZA (100 mg daily...

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Veröffentlicht in:	Arthritis and rheumatism 1991-08, Vol.34 (8), p.961-972
Hauptverfasser:	Jeurissen, Maurice E. C., Th. Boerbooms, Agnes M., Van De Putte, Levinus B. A., Doesburg, Wim H., Mulder, Jan, Rasker, Johannes J., Kruijsen, Marijn W. M., Haverman, Joost F., Van Beusekom, Henk J., Muller, Wim Hissink, Franssen, Marcel J. A. M., De Rooy, Dirk‐Jan R. A. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex Hormones - therapeutic use Adult Aged Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Arthritis, Rheumatoid - blood Arthritis, Rheumatoid - drug therapy Arthritis, Rheumatoid - pathology Azathioprine - standards Azathioprine - therapeutic use Azathioprine - toxicity Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents Double-Blind Method Female Humans Immunoglobulin A - analysis Immunoglobulin G - analysis Immunoglobulin M - analysis Male Medical sciences Methotrexate - standards Methotrexate - therapeutic use Methotrexate - toxicity Middle Aged Pharmacology. Drug treatments Time Factors
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