Etanercept versus methotrexate in patients with early rheumatoid arthritis: Two‐year radiographic and clinical outcomes

Objective To compare the clinical and radiographic outcomes in patients with rheumatoid arthritis (RA) who received monotherapy with either etanercept or methotrexate (MTX) for 2 years and to assess the safety of this therapy. Methods In the Enbrel ERA (early rheumatoid arthritis) trial, 632 patient...

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Veröffentlicht in:	Arthritis and rheumatism 2002-06, Vol.46 (6), p.1443-1450
Hauptverfasser:	Genovese, Mark C., Bathon, Joan M., Martin, Richard W., Fleischmann, Roy M., Tesser, John R., Schiff, Michael H., Keystone, Edward C., Wasko, Mary Chester, Moreland, Larry W., Weaver, Arthur L., Markenson, Joseph, Cannon, Grant W., Spencer‐Green, George, Finck, Barbara K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antirheumatic Agents - administration & dosage Antirheumatic Agents - adverse effects Arthritis, Rheumatoid - diagnostic imaging Arthritis, Rheumatoid - drug therapy Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents Disability Evaluation Disease Progression Double-Blind Method Etanercept Female Humans Immunoglobulin G - administration & dosage Immunoglobulin G - adverse effects Male Medical sciences Methotrexate - administration & dosage Methotrexate - adverse effects Middle Aged Patient Dropouts Pharmacology. Drug treatments Radiography Receptors, Tumor Necrosis Factor - administration & dosage Treatment Outcome
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