Synthesis and Antiinflammatory Activities of Some 2,3‐Dihydro‐1 H ‐benz[ e ]indene‐1‐ and ‐3‐carboxylic Acids

As conformationally rigid analogues of 1‐ and 2‐naphthylacetic acids, some 2,3‐dihydro‐1 H ‐benz[ e ]indene‐1‐ and ‐3‐carboxylic acids were synthesized and tested for antiinflammatory activity by the carrageenin‐induced edema method in rats. Compound (±) 8 was the most active in this series. Synthes...

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Veröffentlicht in:Archiv der Pharmazie (Weinheim) 1983-01, Vol.316 (4), p.309-315
Hauptverfasser: Roveri, Paola, Cavrini, Vanni, Gatti, Rita, Cesaroni, Maria R., Pappalardo, Maria S., Candeletti, Sanzio
Format: Artikel
Sprache:eng
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