Isolation and Characterization of Mammalian Otic Progenitor Cells that Can Differentiate into Both Sensory Epithelial and Neuronal Cell Lineages

ABSTRACT The mammalian inner ear mediates hearing and balance and during development generates both cochleo‐vestibular ganglion neurons and sensory epithelial receptor cells, that is, hair cells and support cells. Cell marking experiments have shown that both hair cells and support cells can origina...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Anatomical record (Hoboken, N.J. : 2007) N.J. : 2007), 2020-03, Vol.303 (3), p.451-460
Hauptverfasser:	Kojima, Ken, Nishida, Akiko T., Tashiro, Kei, Hirota, Kiichi, Nishio, Takeshi, Murata, Miyahiko, Kato, Nobuo, Kawaguchi, Saburo, Zine, Azel, Ito, Juichi, Water, Thomas R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anatomy & Morphology Animals Balance Basic Helix-Loop-Helix Transcription Factors - metabolism Cell culture Cell differentiation Cell Differentiation - physiology Cell Lineage - physiology Cell lines Cell proliferation Cell therapy Cyclin-dependent kinase inhibitor p27 Cytokeratin Ear, Inner - cytology Ear, Inner - embryology Ear, Inner - metabolism Embryos Epithelial cells Epithelium ganglion cell Hair cells Hair Cells, Auditory - cytology Hair Cells, Auditory - metabolism Inner ear Life Sciences & Biomedicine Math1 protein Molecular modelling multipotent progenitor Myosin Myosin VIIA Myosin VIIa - metabolism Nanog Homeobox Protein - metabolism Nestin Nestin - metabolism Neural stem cells NeuroD protein Neurons - cytology Neurons - metabolism Otic epithelium otocyst Progenitor cells Rats Rats, Wistar Science & Technology sensory epithelia Sensory neurons Stem Cells - cytology Stem Cells - metabolism Vestibular ganglion Vestibular system
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!