Macrocyclic Schiff Base Complexes of Zn(II), Cu(II), Co(II), and Ni(II) Targeting Topoisomerase IIβ: Synthesis, Docking, and Evaluation as Potential Anticancer Agents

This study explores the potential of newly synthesized macrocyclic Schiff base metal complexes containing Zn(II), Cu(II), Ni(II) and Co(II) ions as Topoisomerase IIβ inhibitors. The complexes were derived from the condensation of 2,3‐diamino‐5‐bromopyridine and 2,5‐thiophenedicarboxaldehyde. Their f...

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Veröffentlicht in:Applied organometallic chemistry 2024-11
Hauptverfasser: Yadav, Monika, Yadav, Deepak, Singh, Dharam Pal, Kapoor, Jitander Kumar
Format: Artikel
Sprache:eng
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