Aerobic fitness in patients with fibrositis. A controlled study of respiratory gas exchange and 133 xenon clearance from exercising muscle

Aerobic fitness was evaluated in 25 women with fibrositis, by having them exercise to volitional exhaustion on an electronically braked cycle ergometer. Compared with published standards, >80% of the fibrositis patients were not physically fit, as assessed by maximal oxygen uptake. Compared with...

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Veröffentlicht in:Arthritis Rheum.; (United States) 1989-04, Vol.32 (4), p.454-460
Hauptverfasser: Bennett, Robert M., Clark, Sharon R., Goldberg, Linn, Nelson, Donna, Bonafede, R. Peter, Porter, John, Specht, David
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container_issue 4
container_start_page 454
container_title Arthritis Rheum.; (United States)
container_volume 32
creator Bennett, Robert M.
Clark, Sharon R.
Goldberg, Linn
Nelson, Donna
Bonafede, R. Peter
Porter, John
Specht, David
description Aerobic fitness was evaluated in 25 women with fibrositis, by having them exercise to volitional exhaustion on an electronically braked cycle ergometer. Compared with published standards, >80% of the fibrositis patients were not physically fit, as assessed by maximal oxygen uptake. Compared with matched sedentary controls, fibrositis patients accurately perceived their level of exertion in relation to oxygen consumption and attained a similar level of lactic acidosis, as assessed by their respiratory quotient and ventilatory threshold. Exercising muscle blood flow was estimated by 133 xenon clearance in a subgroup of 16 fibrositis patients and compared with that in 16 matched sedentary controls; the fibrositis patients exhibited reduced 133 xenon clearance. These results indicate a need to include aerobic fitness as a matched variable in future controlled studies of fibrositis and suggest that the “detraining phenomenon” may be of relevance to the etiopathogenesis of the disease.
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ispartof Arthritis Rheum.; (United States), 1989-04, Vol.32 (4), p.454-460
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source Wiley Online Library Journals Frontfile Complete; Alma/SFX Local Collection
subjects 550601 - Medicine- Unsealed Radionuclides in Diagnostics
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BLOOD FLOW
CLEARANCE
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DISEASES
ELEMENTS
EVEN-ODD NUCLEI
EXERCISE
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
MAN
MUSCLES
NONMETALS
NUCLEI
OXYGEN
PATIENTS
PRIMATES
RADIOISOTOPES
RADIOLOGY AND NUCLEAR MEDICINE
RESPIRATORY SYSTEM DISEASES
VERTEBRATES
XENON 133
XENON ISOTOPES
title Aerobic fitness in patients with fibrositis. A controlled study of respiratory gas exchange and 133 xenon clearance from exercising muscle
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