Inside Back Cover: Synthesis of a Pentasaccharide Repeating Unit of Lipopolysaccharide Derived from Virulent E. coli O1 and Identification of a Glycotope Candidate of Avian Pathogenic E. coli O1 (Angew. Chem. Int. Ed. 4/2021)

Identification of the glycotope of avian pathogenic E. coli (APEC) O1 is important for the design of a new generation of improved and safer vaccines. In their Research Article on page 1789, Daisuke Takahashi, Kazunobu Toshima, and co‐workers synthesize the unique pentasaccharide derived from virulen...

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Veröffentlicht in:Angewandte Chemie International Edition 2021-01, Vol.60 (4), p.2167-2167
Hauptverfasser: Nishi, Nobuya, Seki, Katsunori, Takahashi, Daisuke, Toshima, Kazunobu
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creator Nishi, Nobuya
Seki, Katsunori
Takahashi, Daisuke
Toshima, Kazunobu
description Identification of the glycotope of avian pathogenic E. coli (APEC) O1 is important for the design of a new generation of improved and safer vaccines. In their Research Article on page 1789, Daisuke Takahashi, Kazunobu Toshima, and co‐workers synthesize the unique pentasaccharide derived from virulent E. coli O1 and reveal that the pentasaccharide is a glycotope candidate of APEC O1, with great potential as an antigen for vaccine development.
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subjects avian pathogenic Escherichia coli
boron-mediated aglycon delivery
glycoconjugate
glycotope
β-rhamnoside
title Inside Back Cover: Synthesis of a Pentasaccharide Repeating Unit of Lipopolysaccharide Derived from Virulent E. coli O1 and Identification of a Glycotope Candidate of Avian Pathogenic E. coli O1 (Angew. Chem. Int. Ed. 4/2021)
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